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Reduced Racial Disparity in Outcomes of Kidney Transplant Recipients Reduced Racial Disparity in Outcomes of Kidney Transplant Recipients
*E IRANPOUR, *A TAVABI, *R GOHH, P MORRISSEY, REZA SAIDI
BROWN U, PROVIDENCE, RI
Reduced Racial Disparity in Outcomes of Kidney Transplant Recipients
Iranpour E, Tavabi A, Garakani, R, Gohh R, Morrissey P, Saidi R
Division of Organ Transplantation, Department of Surgery, Rhode Island Hospital, Alpert Medical School of Brown University, Providence, RI
OBJECTIVE: Earlier studies reported inferior outcomes among African-American (AA) compared with white kidney transplant (KT) recipients.
DESIGN: Prospective database.
SETTING: Single center.
PATIENTS: During 1997-2015, 1102 patients underwent KT at our center. Hispanics, pediatric patients and recipients of multi-organ transplants were excluded.
MAIN OUTCOME MEASURES: We examined the renal allograft survival in two eras; 1997-2005 and 2006-2015.
RESULTS : AA and white recipients did not differ in age, gender or time to transplantation. AA had inferior 5- year allograft survival compare to whites; 67.8 vs 76.2%, respectively (p<0.001). However, comparing era-1 (1997-2005) with era-2 (2006-2015), we noted an improvement in allograft survival in AAs recipients; 65.1 vs 78.1%, respectively (p<0.001). The allograft survival in era-2 was comparable between AA and whites. Allograft survival in whites was comparable between era-1 and era-2 (76.8 vs 78.1%). Allograft survival in AA who received LDKT did not improved comparing era-1 and era-2 (76.4 vs 77.9%). However, allograft survival in AA who received DDKT improved during era-2 compare to era-1; 73.6 vs 66.4%, respectively (p=0.009).
CONCLUSIONS: In era 2, we observed no disparity in AA outcomes compared with whites. This result should promote access to KT in AA patients. Further studies are needed to determine the reasons for improved outcomes for AA in recent years.
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