Back to 2016 Annual Meeting Posters
Use of Hyperspectral Imaging to Assess Vascular Dysfunction in Patients with Diabetes
*Gianluca Citoni, *Brandon Sumpio, *Jason Chin, Bauer Sumpio
Yale University, New Haven, CT
Objective:
The aim of this pilot study was to determine if HSI could be used to demonstrate the role of Diabetes Mellitus in the upper extremity of patients with peripheral artery disease (PAD) or coronary artery disease (CAD). Design:
prospective study.
Setting:
Out-patient
Patients:
48 consented patients during a 16-week period with diagnosed PAD or CAD with or without Diabetes Mellitus
Interventions:
Patients underwent HSI at the bicep, forearm, and palm before and after cuff occlusion (50 mmHg above systolic) for 5 minutes. The absolute and percent changes in oxyHb and deoxyHb levels were assessed. Medical records of enrolled patients were reviewed for demographic data, medications, surgical history, and other pertinent information. Patients were separated into PAD or CAD with diabetes and PAD or CAD without diabetes. Baseline differences in categorical variables of medical history were evaluated using the chi-square test. Differences in HSI values between the groups were evaluated using the two-tailed t- test with statistical significance determined as P<0.05. Main Outcome Measures: The absolute and percent changes in oxyHb and deoxyHb levels were assessed.
Results:
The study enrolled 22 diabetic patients and 26 patients without diabetes. The distinct groups had comparable values at baseline. No differences were noted for oxyHb and deoxyHb values in all of the different evaluated areas. Conclusions:
This study presents a novel way to measure endothelial dysfunction similarly to the brachial artery reactivity test. Our results suggest the capability of HSI technology to be not influenced by Diabetes Mellitus in PAD or CAD patients. This could enable early screening and tracking of PAD or CAD patients in a diabetic cohort.
Back to 2016 Annual Meeting Posters
